SemmelweisBuild and Guide

Character
Introduction

Semmelweis is a 6 rarity character from the Mineral afflatus who deals Reality damage and belongs to the Support class.

Fittingly enough for a vampire, Semmelweis drains the HP of her allies in exchange for granting potent offensive buffs. Upon targeting an ally with the [Fresh Blood] buff, the whole team gains +DMG Dealt% while targeted ally gains extra Crit Rate when attacking at the price of some HP. Semmelweis' Ultimate drains the whole team's HP to set up the [Blood Domain] Array, which grants allies +Damage Dealt proportional to their percentage of lost HP. Semmelweis pairs well with characters with self-damage effects, but she also requires hefty sustain to ensure the survival of the team.

To learn more about Semmelweis check the sections below. Use the tabs to quickly switch to the kind of information you're looking for.

Video guide

This character has no video guide yet.

Last updated

Semmelweis profile was last updated on November 14th, 2024.

To learn more about Semmelweis check the sections below. Use the tabs to quickly switch to the kind of information you're looking for.

Profile

Review

Stats & Build

Synergy & Teams

Lore

Profile

Specialties
Support
DPS
Blood Burn
Skills
As the Moon Rises
Skill

Mass Buff. All allies lose (Current HP x20%) HP. Creates a special array [Blood Domain] for 3 rounds; Enters [Feral] status for 3 rounds.

It was on this night that she turned. She will remain what she's become tomorrow, and in the rest of her life."

Blood Domain

[Array] effect: Allied characters gain DMG Taken Reduction +20%. Whenever an ally attacks, for every 10% of their missing HP, gain DMG Bonus +5% (up to 40%).

Feral

At the end of the round, casts [Truth Revealed] if still under the [Feral] status.

Truth Revealed

Mass Attack. Deals 80% Reality DMG to all enemies.

Iron Nameplate
Skill

✧✧

[Attack]

1-Target attack. Loses (Current HP x10%) HP and deals 220% Reality DMG.

It watches her six."

✦✦

[Attack]

1-Target attack. Loses (Current HP x10%) HP and deals 330% Reality DMG.

It watches her six. Not a reliable ally, though."

✦✦✦

[Attack]

1-Target attack. Loses (Current HP x10%) HP and deals 550% Reality DMG.

It watches her six. Not a reliable ally, but better than nothing."
Proper Means
Skill

✧✧

[Buff]

1-Target Buff. Grants the [Fresh Blood] status to 1 ally for 2 rounds. Then grants DMG Dealt +15% to all allies and additional DMG Dealt +10% to the ally in [Fresh Blood] for 2 rounds.

Let the moon witness her transfer."

✦✦

[Buff]

1-Target Buff. Grants the [Fresh Blood] status to 1 ally for 2 rounds. Then grants DMG Dealt +20% to all allies and additional DMG Dealt +10% to the ally in [Fresh Blood] for 2 rounds.

Let the moon witness her transfer and hypocrisy."

✦✦✦

[Buff]

1-Target Buff. Grants the [Fresh Blood] status to 1 ally for 2 rounds. Then grants DMG Dealt +30% to all allies and additional DMG Dealt +10% to the ally in [Fresh Blood] for 2 rounds.

Let the moon witness her transfer and hypocrisy, and the only hope hidden behind her madness."

Fresh Blood

Right before actively casting an incantation, lose (Current HP x5%) HP to grant Critical Rate +15% to this action. Only 1 [Fresh Blood] can exist on the allied side at a time.

Inheritance
Insight 1
Blood Thirst
Insight I

When entering battle, loses (own Current HP x20%) and gains Moxie +3.

Materials
  • Sharpodonty
    Sharpodontyx18000
  • Page of Mineral Wealth
    Page of Mineral Wealthx6
  • Trembling Tooth
    Trembling Toothx5
  • Rough Silver Ingot
    Rough Silver Ingotx5
Insight 1
Blood Thirst
Insight II

DMG Dealt +8% when the caster enters battle.

Materials
  • Sharpodonty
    Sharpodontyx40000
  • Scroll of Mineral Wealth
    Scroll of Mineral Wealthx10
  • Cicada Wingsx6
  • Bifurcated Skeleton
    Bifurcated Skeletonx6
Insight 1
Blood Thirst
Insight III

Right after casting an Ultimate, loses (own Current HP x10%) HP and gains Moxie +1. When in the [Feral] status, for every HP loss effect suffered by any characters when an ally takes an action, this [Truth Revealed] deals an additional Reality DMG +30% (up to 20 stacks for each attack).

Materials
  • Sharpodonty
    Sharpodontyx200000
  • Tome of Mineral Wealth
    Tome of Mineral Wealthx16
  • Murmur of Insanity
    Murmur of Insanityx6
  • Fruit of Good and Evil
    Fruit of Good and Evilx3
Special effects

Feral

At the end of the round, casts [Truth Revealed] if still under the [Feral] status.

Truth Revealed

Mass Attack. Deals 80% Reality DMG to all enemies.

Euphoria

Semmelweis doesn't have an Euphoria update yet. If it will be released, we will add it here.

Portray
Semmelweis Portray
Portray details

Lv. 1

As the Moon Rises: Deployed [Blood Domain]'s effect is now: Whenever an ally attacks, for every 10% of their missing HP, gain DMG Bonus +7.5% (up to 60%).

Lv. 2

Blood Thirst: When in the [Feral] status, the effect changes to: for every HP loss effect suffered by any characters when an ally takes action, this [Truth Revealed] deals an additional Reality DMG +45%.

Lv. 3

As the Moon Rises: When in the [Feral] status, [Truth Revealed] Reality DMG dealt to all enemies increased to 120%.

Lv. 4

Iron Nameplate: Reality DMG increased to 260/390/630%.

Lv. 5

Blood Thirst: When in the [Feral] status, the effect changes to: for every HP loss effect suffered by any characters when an ally takes action, this [Truth Revealed] deals an additional Reality DMG +60%.

Gallery

Review

Review

Semmelweis is a 6-star Mineral Reality character who functions as an damage-buffing Support. She provides powerful buffs at the cost of HP—a kit befitting of a vampire.

Semmelweis’ buff incantation “Proper Means” grants everyone a DMG Dealt buff and allows her to designate one ally as [Fresh Blood]: before actively casting an incantation, this ally loses some HP and gains +15% Critical Rate for this action. Semmelweis drains her own HP, too—her basic attack “Iron Nameplate” has very high multipliers at the cost of 10% of her Current HP.

All of these instances of HP drain allow Semmelweis’ teammates to take full advantage of her [Blood Domain] Array. Under [Blood Domain], allied characters gain DMG Taken Reduction and +5% DMG Bonus for each 10% of their HP they are missing. Semmelweis creates this Array through her Ultimate, “As the Moon Rises,” which drains 20% of all allies’ Current HP and causes her to enter the [Feral] status for 3 rounds—the same duration as her Array. During these 3 rounds, [Feral] causes Semmelweis to cast a mass attack [Truth Revealed] at the end of each round. [Truth Revealed] scales by +30% Reality DMG per instance of HP loss when characters take action, stacking up to a whopping +600% for a total multiplier of 680% at 20 stacks (which is admittedly very difficult to achieve).

A powerful support whose DMG Bonus and Critical Rate buffs can aid the vast majority of DPS characters, Semmelweis is a universally applicable teammate for players looking to increase their team’s damage in exchange for survivability. Semmelweis also enables the new self-damage team archetype by providing a potent payoff for HP drain through [Blood Domain]’s strong DMG Bonus scaling. Although primarily an offensive support, Semmelweis certainly doesn’t lack in the damage department herself. On top of that, Semmelweis has plenty of Moxie to set up her Array. Her Insight I continues the trend of Ultimate-Array casters gaining +3 Moxie when entering battle first seen in Getian’s kit. However, unlike her predecessor, she gains +1 Moxie upon casting her Ultimate, allowing her to comfortably recast her Array every 3 turns without needing to move incantations or refresh her 2-turn buff prematurely.

By casting her buff and attack incantations on Round 1, Semmelweis can cast her Ultimate as early as Round 2. After that, she can achieve 100% uptime on [Blood Domain] by reapplying [Fresh Blood] every other turn and attacking 2–3 times between each Ultimate to replenish Moxie.

In conclusion, Semmelweis is a formidable Support character who is relatively simple to play. If you have some extra Stamina, like playing self-damaging characters, or are in need of some extra damage, consider building your free copy of Semmelweis.

Pros & Cons
Pros

  • Universal support with powerful DMG Bonus and Crit Rate buffs.

  • Array effect stacks with other status effects.

  • High personal damage multipliers and access to both AoE and single-target attacks. Can apply [Fresh Blood] to herself for a more DPS playstyle.

  • Synergizes well with self-damaging characters, giving new life to old characters like Eternity.

  • Simple rotation and easy-to-maintain Array.

  • Free in 1.9!

Cons

  • High HP tax that requires a substantial amount of sustain; makes your team more vulnerable to burst damage.

  • Not that many self-damaging characters available as of 1.9, so stacking up [Truth Revealed] takes time.

  • Not the most AP-positive—casts around 2 incantations per round for 100% uptime. HP drain may mean your Survival unit also needs to use more AP to keep team alive.

Ratings

Fittingly enough for a vampire, Semmelweis drains the HP of her allies in exchange for granting potent offensive buffs. Upon targeting an ally with the [Fresh Blood] buff, the whole team gains +DMG Dealt% while targeted ally gains extra Crit Rate when attacking at the price of some HP. Semmelweis' Ultimate drains the whole team's HP to set up the [Blood Domain] Array, which grants allies +Damage Dealt proportional to their percentage of lost HP. Semmelweis pairs well with characters with self-damage effects, but she also requires hefty sustain to ensure the survival of the team.

A+

Overall

A+

Overall (Euphoria)

Stats and Build

Resonance

For Resonance, we have created a dedicated website to browse them easier. You can find the website here:

Psychubes
Comments

Obtainable from the 2.0 roguelike mode, “From the Depths” is Semmelweis’ signature psychube. Because her Ultimate damages all allies, it can activate this psychube’s passive and grant Semmelweis the [Echoes of Life] status, which sets her to 33% HP after taking lethal damage. Each instance of self-damage on the team increases the carrier’s Incantation Might; at maximum stacks, the psychube offers a truly enormous +39% Incantation Might. This psychube also offers excellent Reality DEF and Mental DEF, making Semmelweis more resistant to damage.

“Long Night Talk” is a decent option for Semmelweis, especially if you already have it built. While she cannot activate the “2+ [Pos Status]” passive on her own ([Feral] counts, but [Fresh Blood] is Special), she does cast a lot of buffs and benefits from the ATK% increase. Semmelweis also makes good use of its base 18% Incantation Might.

As always, “Blasphemer of Night” is a good damage option if you can activate its conditions. Semmelweis doesn’t inflict any [Neg Status] on her own, but she benefits from the Incantation Might, though the extra DMG Dealt might reach diminishing returns.

Available in 1.9 from her Anecdote, “In the Shadow” is a tailored 5-star option for Semmelweis. At full stacks, it offers a very solid 12% DMG Reduction, +10% ATK, and 15% Incantation Might. Be warned, however: this is a hyper-specific psychube that can only be fully utilized by Semmelweis (and Bette, weirdly enough).

Stats
STAT

Base

Level 1

Level 30

Insight 1

Level 1

Level 40

Insight 2

Level 1

Level 50

Insight 3

Level 1

Level 60

ATK
ATK

254

385

424

646

685

963

999

1133

ATK
HP

1360

2064

2276

3461

3673

5161

5355

6072

ATK
Reality DEF

128

194

213

326

345

486

504

572

ATK
Mental DEF

128

194

213

326

345

486

504

572

ATK
Critical Technique

273

273

309

309

345

345

381

381

ATK
Critical Rate

9.1%

9.1%

10.3%

10.3%

11.5%

11.5%

12.7%

12.7%

ATK
Critical DMG

143.7%

143.7%

145.4%

145.4%

147.3%

147.3%

149.1%

149.1%

Synergy & Teams

Synergy & Teams

Semmelweis Synergy & Teams information aren't available yet. They will be added soon!

Lore

Lore

Semmelweis Lore information aren't available yet. They will be added soon!